Metal Complexes in Target-Specific Anticancer Therapy: Recent Trends and Challenges
نویسندگان
چکیده
Cancer is characterized by abnormal cell differentiation in or on the part of body. The most commonly used chemotherapeutic drugs are developed to target rapidly dividing cells, such as cancer but they also damage healthy epithelial cells. This has serious consequences for normal cells and become responsible development various disorders. Several strategies delivering cytotoxic cancerous sites that limit systemic toxicity other adverse effects have recently been evolved. Among them, biomolecule-conjugated metal complexes-based targeting shown tremendous advantages therapy. review focuses several chemoselective biomolecules-bound complexes prospective therapy-targeted agents. In this review, we presented details extra- intracellular mechanisms We addressed current clinical issues recent therapeutic targeted therapy may pave a way future direction
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ژورنال
عنوان ژورنال: Journal of Chemistry
سال: 2022
ISSN: ['2090-9063', '2090-9071']
DOI: https://doi.org/10.1155/2022/9261683